Thyroid and adrenal disorders

Non-diabetes endocrine items ask you to name whether metabolism is racing or stalled, whether cortisol is missing or flooding, and which drug or crisis kills first. Diabetes and insulin live in Diabetes and glycemic emergencies — this chapter owns thyroid, adrenal, and the pituitary urine disorders that sit next to sodium teaching.

Thyroid: hypo vs hyper

Thyroid hormone sets the metabolic throttle. Too much hormone (hyperthyroidism, often Graves or over-replacement) burns fuel fast: heat intolerance, weight loss despite appetite, tachycardia, tremor, anxiety, and sometimes eye findings. Too little (hypothyroidism, Hashimoto or undertreatment) slows everything: cold intolerance, weight gain, bradycardia, constipation, dry skin, and dull thinking. The exam ask is matching the picture to the environment and the first safety move — not memorizing every lab code.

At the bedside, hyperthyroid care is about lowering stimulus and cardiac demand while ordered antithyroid therapy works. Hypothyroid care is about supporting a slow heart and brain without pretending a warm blanket fixes missing hormone. Post-thyroidectomy stems add airway and calcium watch: hematoma or laryngeal edema can close the airway, and accidental parathyroid injury drops calcium with tetany and laryngospasm risk — calcium rules live with electrolytes, but the airway check is yours in the moment.

• After thyroidectomy: semi-Fowler, support the neck, watch for stridor/bleeding behind the dressing, keep tracheostomy tray available per protocol.
• Tingling around the mouth or Chvostek/Trousseau after thyroid surgery → think hypocalcemia; notify and follow calcium orders.
• Do not massage a fresh thyroid incision or flex the neck hard against orders.

Thyroid crises and drugs

Thyroid storm is uncontrolled hyperdrive — often triggered by infection, surgery, or stopping antithyroid meds. Fever, extreme tachycardia, vomiting, and agitation or delirium mean the client can tip into cardiovascular collapse. Myxedema coma is the opposite extreme: profound hypothyroidism with hypothermia, bradycardia, hypoventilation, and falling LOC. Both are emergencies; the distractor is treating either as “anxiety” or “just tired.”

1. Thyroid storm: airway/O2, cardiac monitor, cooling measures, ordered antithyroid + iodine sequence, beta-blocker as ordered — do not leave for oral teaching alone.
2. Myxedema: protect airway and breathing, gentle rewarming, IV thyroid hormone and steroids as ordered, avoid sedatives that deepen coma.
3. Never force rapid external heating that burns skin while the core is still cold.

Levothyroxine replaces missing hormone. Teach empty-stomach mornings, consistent timing, and separating doses from calcium, iron, and antacids that bind the drug in the gut. Report chest pain, palpitations, or nervousness that suggest over-replacement. Antithyroid drugs (methimazole, PTU) block new hormone synthesis — fever or sore throat can signal agranulocytosis and needs an immediate hold-and-call, not “wait for the next appointment.” Radioactive iodine and surgery pathways need isolation or airway teaching as ordered; iodine solutions taken orally need a straw and dental care teaching when the product stains.

Adrenal: Addison vs Cushing

The adrenal cortex makes cortisol (stress hormone, glucose, immune tone) and aldosterone (sodium retain, potassium dump). Addison disease is underproduction: the client looks bronze or tanned in sun-exposed areas, runs low blood pressure, low sodium, high potassium, and can crash into shock when stressed without enough steroid cover. Cushing syndrome is cortisol excess (tumor or chronic steroid therapy): moon face, truncal obesity, thin fragile skin, hyperglycemia, and infection risk. Name which side of the cortisol seesaw you are on before you pick fluids, steroids, or infection precautions.

Addisonian crisis is distributive-style shock with the electrolyte fingerprint above. Give ordered IV fluids and glucocorticoids (and mineralocorticoid when indicated); treat the precipitating stress. Lifelong replacement teaching includes stress dosing when sick or before procedures as the provider directs — the caring-looking wrong answer is holding the morning steroid because the client “feels fine.” Cushing care is mechanical protection and metabolic watch: turn gently, protect skin, monitor glucose, and treat steroids as infection risk, not as a harmless energy pill.

• Medic-alert and stress-dose teaching belong with Addison replacement.
• Sudden stop of long-term steroids can precipitate adrenal insufficiency — taper only as ordered.
• Cushing: report fever early; skin tears and poor wound healing are expected traps.

Pituitary urine disorders: DI vs SIADH

Antidiuretic hormone (ADH, vasopressin) tells the kidney to hold water. Diabetes insipidus is too little ADH effect: huge dilute urine, rising serum sodium risk, and thirst. SIADH is too much ADH effect: the body holds water, urine concentrates, and serum sodium falls — seizure risk. Fluid restriction and sodium correction for SIADH, and the food-plate sodium teaching, live in Electrolytes and Fluid volume imbalances. This chapter’s job is to recognize the DI picture and the ADH direction so you do not fluid-load the wrong client.

After pituitary surgery or head injury, sudden polyuria is DI until proven otherwise — match intake to output, watch sodium, and give ordered desmopressin. The distractor is treating DI like SIADH with free-water restriction, or treating SIADH with free water boluses “because they look dry.”

Priority map